The Relationship Between Blast-Related Mild Traumatic Brain Injury and Executive Function is Associated with White Matter Integrity

Authors

Molly C. O'Brien, Macalester CollegeFollow

Document Type

Honors Project

Abstract

This project details the outcomes of mild traumatic brain injury (mTBI) including injury mechanism, immunological response, and cognitive performance. The study investigates if the integrity of certain brain regions influences the association between remote mTBI and executive function. Based on data from 182 veterans from the Minneapolis VA Medical Center, an association between blast injury severity and executive function was found to be moderated by white matter integrity of the right hippocampal cingulum in veterans with blast exposure history, such that those with higher blast severity showed a greater effect of the association between lower integrity and worse performance.

Recommended Citation

O'Brien, Molly C., "The Relationship Between Blast-Related Mild Traumatic Brain Injury and Executive Function is Associated with White Matter Integrity" (2022). Neuroscience Honors Projects. 1.
https://digitalcommons.macalester.edu/neurosci_honors/1